Genetic polymorphisms in Kawasaki disease
نویسندگان
چکیده
منابع مشابه
COVID-19 and Kawasaki Disease: Kawasaki-Like Disease Case Report in Iran
During the Coronavirus disease 2019 (COVID-19) pandemic, children are less affected than adults, and underlying conditions and older age are associated with severe disease. Following the SARS-CoV-2 pandemic, outbreaks of cases with Kawasaki-like disease and a few others with the multisystem inflammatory syndrome in children related to COVID-19 (MIS-C) have been reported. Here, we report a two-y...
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Kawasaki disease (KD) is the most common cause of pediatric acquired heart disease. KD patients have spontaneously high plasma/serum levels of IL-10 during the acute phase. Therefore, two independent studies were carried out to investigate the association between genetic variants in IL-10 promoter (-1082, -819, and -592) and risk of KD. A total of 134 trios were included for the family-based as...
متن کاملInterleukin-21 Receptor Gene Polymorphisms in Kawasaki Disease
BACKGROUND AND OBJECTIVES Interleukin-21 receptor (IL-21R) gene polymorphism is related with the development of systemic vasculitis. In this study, we investigated the polymorphisms of IL-21R gene in patients with Kawasaki disease (KD). SUBJECTS AND METHODS We genotyped the promoter region of IL-21R gene (-2500 bp to +1 bp) in 100 patients with KD and 100 healthy controls. All study subjects ...
متن کاملKawasaki Disease in Children: A Case Report.
SUMMARY: Kawasaki is an acute multisystemic disease affecting Predominantly. Children below 4 years of age. Having a Self- limited Course, it often Presents as Vasculitis. The Principal Complications are Stomatitis, conjunctivitis. Lymphadenopathy, Skin rashes as well as involvment of cardiovascular, alimentary and nervous system. In this article we report the First case of Kawasaki Disease ...
متن کاملConsortium-Based Genetic Studies of Kawasaki Disease in Korea: Korean Kawasaki Disease Genetics Consortium
In order to perform large-scale genetic studies of Kawasaki disease (KD) in Korea, the Korean Kawasaki Disease Genetics Consortium (KKDGC) was formed in 2008 with 10 hospitals. Since the establishment of KKDGC, there has been a collection of clinical data from a total of 1198 patients, and approximately 5 mL of blood samples per patient (for genomic deoxyribonucleic acid and plasma isolation), ...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2011
ISSN: 1671-4083,1745-7254
DOI: 10.1038/aps.2011.93